The Impact of a High-Fat Diet on Blood Glucose Levels

Abstrak

ABSTRACT
Background: Diabetes mellitus (DM) sufferers in the world and even in
Indonesia are expected to continue to increase, especially type 2 DM
(DMT2). DMT2 often occurs in people who are obese, the cause of obesity
is often consuming foods that contain a lot of fat. Hyperlipidemia plays a
role in the pathogenesis of pancreatic β-cell dysfunction.
Research method: This study is an experimental laboratory study with a
pretest-posttest only controlled group design, using male white rats
(Rattus norvegicus) with a sample size of 30 divided into 6 groups, namely
the normal group, the negative control group, the positive control group,
the group given a high fatty diet (HFD). The independent variable is HFD,
while the dependent variable is blood sugar levels. Data were analyzed
using the Anova test.
Results: Giving HFD of 4 ml/day for 4 weeks has not been able to increase
KGD to hyperglycemic, this is thought to be because the HFD was not
given for long enough so that insulin resistance had not occurred in the
test animals.
Conclusion: Based on the results of the study, it was concluded that giving
HFD for 4 weeks still could not increase KGD in male white mice to
become hyperglycemic.
Keywords: : Diabetes Mellitus, Blood Sugar Levels, High Fatty Diet